Salim T. Islam, Israel Vergara Alvarez, Fares Saïdi, Annick Giuseppi, Evgeny Vinogradov, Castrese Morrone, Gael Brasseur, Gaurav Sharma, Anaïs Benarouche, Jean-Luc Bridot, Gokulakrishnan Ravicoularamin, Alain Cagna, Charles Gauthier, Mitchell Singer, Henri-Pierre Fierobe, Tâm Mignot, Emilia Mauriello. Modulation of bacterial multicellularity via spatiotemporal polysaccharide secretionbioRxiv, 2020, doi: https://doi.org/10.1101/2020.02.20.957654


Whitfield DL#, Sharma G#, Smaldone GT, Singer M. 2019. Peripheral rods: a specialized developmental cell type in Myxococcus xanthus. Genomics. 2019 Oct 9;. doi: 10.1016/j.ygeno.2019.09.008. https://www.sciencedirect.com/science/article/pii/S0888754319302472    #Equal Authors


Islam Salim T., Belgrave Akeisha M., Fleuchot Betty, Jolivet Nicolas Y., My Laetitia, Faure Laura M., GauravSharma, Lemon David J., Fiche Jean-Bernard, Bratton Benjamin T., MitchellSinger, Garza Anthony G., Nöllmann Marcelo, Shaevitz Joshua W., Mignot Tâm Integrin-Like Tethering of Motility Complexes at Bacterial Focal Adhesions (2018). Available at SSRN: https://ssrn.com/abstract=3188409 or http://dx.doi.org/10.2139/ssrn.3188409  

Sharma G*, Parales R, and Singer M*. 2018. In silico functional characterization of a novel aerotaxis chemosensory system in myxobacterium Corallococcus corraloides, BMC Genomics, 2018, 19:757, https://doi.org/10.1186/s12864-018-5151-6     *corresponding authors

Sharma G*, Burrows LL, and Singer M*. 2018. Diversity and Evolution of Myxobacterial Type IV Pili System, Frontiers of Microbiology, 19 July 2018, https://doi.org/10.3389/fmicb.2018.01630  *corresponding authors


Skotnicka D, Smaldone GT, Petters T, Trampari E, Liang J, Kaever V, Malone JG, Singer M, Søgaard-Andersen L. 2016. A Minimal Threshold of c-di-GMP Is Essential for Fruiting Body Formation and Sporulation in Myxococcus xanthus. PLoS Genet. 2016 May 23;12(5):e1006080. https://www.ncbi.nlm.nih.gov/pubmed/27214040


Smaldone G.T., Jin Y., Whitfield D.L., Mu A.Y., Wong E.C., Wuertz S., Singer M. 2014. Growth of Myxococcus xanthus in continuous-flow-cell bioreactors as a method for studying development. Appl Environ Microbiol. 80(8):2461-7. https://www.ncbi.nlm.nih.gov/pubmed/24509931


Bragg J., Rajkovic A., Anderson C., Curtis R., Van Houten J., Begres B., Naples C., Snider M., Fraga D., Singer M. 2012. Identification and characterization of a putative arginine kinase homolog from Myxococcus xanthusrequired for fruiting body formation and cell differentiation. J Bacteriol. 194(10):2668-76. https://www.ncbi.nlm.nih.gov/pubmed/22389486


Rosario C.J., Singer M. 2010. Developmental expression of dnaA is required for sporulation and timing of fruiting body formation in Myxococcus xanthus. Mol. Microbiol. 76(5):1322-33. https://www.ncbi.nlm.nih.gov/pubmed/20487266


Wu D, Hugenholtz P, Mavromatis K, Pukall R, Dalin E, Ivanova NN, Kunin V, Goodwin L, Wu M, Tindall BJ, Hooper SD, Pati A, Lykidis A, Spring S, Anderson IJ, D’haeseleer P, Zemla A, Singer M, Lapidus A, Nolan M, Copeland A, Han C, Chen F, Cheng JF, Lucas S, Kerfeld C, Lang E, Gronow S, Chain P, Bruce D, Rubin EM, Kyrpides NC, Klenk HP, Eisen JA. 2009. https://www.ncbi.nlm.nih.gov/pubmed/20033048

Bode H.B., Ring M.W., Schwär G., Altmeyer M.O., Kegler C., Jose I.R., Singer M., Müller R. 2009. Identification of Additional Players in the Alternative Biosynthesis Pathway to Isovaleryl-CoA in the Myxobacterium Myxococcus xanthus. Chembiochem. 10(1):128-40. https://www.ncbi.nlm.nih.gov/pubmed/18846531


Rosario C.J., Singer M. 2007. The Myxococcus xanthus developmental program can be delayed by inhibition of DNA replication. J. Bacteriol. 189:8793-8800. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2168630/

Ossa F.*, Diodati M.E.*, Caberoy N.B., Giglio K.M., Edmonds M., Singer M., Garza A.G. 2007. The Myxococcus xanthus Nla4 protein is important for expression of stringent response-associated genes, ppGpp accumulation, and fruiting body development. J. Bacteriol. 189:8474-8483. https://jb.asm.org/content/189/23/8474

Diodati M.E., Gill R.E., Plamann L., Singer M. 2007. “Initiation and Early Developmental Events.” Myxobacteria: Multicellularity and Differentiation (Peer-Reviewed Book Chapter) 43-76. https://www.asmscience.org/content/book/10.1128/9781555815677


Suen, G., J.S. Jakobsen, B.S. Goldman, M. Singer, A.G. Garza and R.D. Welch 2006. Bacterial Postgenomics: the Promise and Peril of Systems Biology J. Bacteriol. 188:7999-8004. https://www.ncbi.nlm.nih.gov/pubmed/16997947

Pham V.D., C.W. Shebelut, I.R. Jose, D. A. Hodgson, D.E. Whitworth and M. Singer. The response regulator PhoP4 is required for late developmental events in Myxococcus xanthus. 2006. Microbiology. 152:1609-20. https://www.ncbi.nlm.nih.gov/pubmed/16735725

Viswanathan, P., M. Singer and L. Kroos. 2006. Role of σD in Regulating Genes and Signals during Myxococcus xanthus Development. J. Bacteriol. 188:3246-3256. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1447441/

Tzeng, L., T.N. Ellis and M. Singer. 2006. DNA Replication during Aggregation Phase Is Essential for Myxococcus xanthus Development. J. Bacteriol. 188:2774-79. https://jb.asm.org/content/188/8/2774

Diodati, M.E., F. Ossa, N.B. Caberoy, I.R. Jose, W. Hiraiwa, M.M. Igo, M. Singer and A.G. Garza. 2006. Nla18, a Key Regulatory Protein Required for Normal Growth and Development of Myxococcus xanthus. J. Bacteriol.188:1733-43. https://jb.asm.org/content/188/5/1733


Tzeng L. and M. Singer. 2005. DNA replication during sporulation in Myxococcus xanthus fruiting bodies. PNAS 102:14428-33. https://www.pnas.org/content/102/40/14428

Pham V.D., C.W. Shebelut, B. Mukherjee and M. Singer. 2005. RasA is required for Myxococcus xanthus development and social motility. J. Bacteriol. 187:6845-48. https://jb.asm.org/content/187/19/6845

Pham V.D., C.W. Shebelut, E.J. Zumstein and M. Singer. 2005. BrgE is a regulator of Myxococcus xanthus development. Molecular Microbiology. 57:762-73. https://onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2958.2005.04726.x

Pham V.D., C.W. Shebelut, M.E. Diodati, C.T. Bull and M. Singer. 2005. Mutations affecting predation ability of the soil bacterium Myxococcus xanthus. Microbiology. 151:1865-74. https://www.ncbi.nlm.nih.gov/pubmed/15941994


Brenner, M., A. Garza and M. Singer. 2004. nsd, a Locus that Affects the Myxococcus xanthus Cellular Response to Nutrient Concentration. J. Bacteriol. 186:3461-3471. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC415774/


Pollack, J. and M. Singer. 2001. SdeK, a Histidine Kinase Required for Myxococcus xanthus Development. J. Bacteriol.. 183:3589-3596. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC95235/


Garza, A.G., B.Z. Harris, J.S. Pollack and M. Singer. 2000. The asgE locus is required for cell-cell signaling during the Myxococcus xanthus development. Mol. Microbiol. 35:812-824. https://www.ncbi.nlm.nih.gov/pubmed/10692158

Garza A.G., B.Z. Harris, B. Greenberg, and M. Singer. 2000. Control of asgE Expression during Growth and Development of Myxococcus xanthus. J. Bacteriol. 182:6622-6629. https://jb.asm.org/content/182/23/6622


Garza A.G., J.S. Pollack, B.Z. Harris, A. Lee, I.M. Keseler, E.F. Licking, and M. Singer. 1998. SdeK Is Required for Early Fruiting Body Development in Myxococcus xanthus. J. Bacteriol. 180:4628-4637. https://www.ncbi.nlm.nih.gov/pubmed/9721305

Harris, B., Kaiser D., and M. Singer. 1998. The guanosine nucleotide (p)ppGpp initiates development and A-factor production in Myxococcus xanthus. Genes & Dev. 12:1022-1035. https://www.ncbi.nlm.nih.gov/pubmed/9531539

Harris, B., and M. Singer. 1998. Identification and Characterization of the Myxococcus xanthus argE Gene. J. Bacteriol. 180:6412-6414. https://jb.asm.org/content/180/23/6412.abstract


Singer, M., and D. Kaiser. 1995. Ectopic production of guanosine penta- and tetraphosphate can initiate early developmental gene expression in Myxococcus xanthus. Genes & Dev. 9:1633-1644. https://www.ncbi.nlm.nih.gov/pubmed/7628697


Stephens, C., M. Singer and L. Shapiro. 1994. An ATP/ADP switch. Current Biology. 4:630-632. https://www.ncbi.nlm.nih.gov/pubmed/7953541


Singer, M., D.J. Jin, W.A. Walter and C.A. Gross. 1993. Genetic Evidence for the Interaction between Cluster I and Cluster III Rifampicin Resistant Mutations. J. Mol Biol. 231:1-5. https://www.ncbi.nlm.nih.gov/pubmed/8496955


Singer, M., W.A. Walter, B.M. Cali, P. Rouviere, H.H. Liebke, R.L. Gourse and C.A. Gross. 1991. Physiological Effects of the Fructose-1,6-Diphosphate Aldolase ts8 Mutation on Stable RNA Synthesis in Escherichia coli. J. Bacteriol. 173:6249-6257. https://www.ncbi.nlm.nih.gov/pubmed/1717436

Singer, M., P. Rossmiessl, B.M. Cali, H. Liebke and C.A. Gross. 1991. The Escherichia coli ts8 Mutation is an Allele of fda, the Gene Encoding Fructose-1,6-Diphosphate Aldolase. J. Bacteriol. 173:6242-6248. https://www.ncbi.nlm.nih.gov/pubmed/1917856